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Bupropion HCL (Wellabutrin) 
DescriptionWellabutrin XL, Zyban ( Bupropion HCL ) uses include: Bupropion SR (Wellbutrin SR), an antidepressant (mood elevator), is used to treat depression. Bupropion SR (Zyban) is used to help people stop smoking.
Bupropion HCL (generic Wellabutrin XL, Zyban) Reviewbrand names: Buproban , Zybangeneric names: Nicotine, Bupropion Sustained-Release, Bupropion hydrochloride, Bupropion Zyban Sustained-Release Tablets is used for:Helping certain patients to stop smoking cigarettes. It may also be used for other conditions as determined by your doctor. Zyban Sustained-Release Tablets is an antidepressant that has been found to aid in the stopping of smoking. What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions: •frequently drink alcoholic beverages •an eating disorder, dyes, foods, other medicines, or irregular heart beat •head injury or brain tumor •high blood pressure •kidney disease •liver disease •seizures (convulsions) •suicidal thoughts or a previous suicide attempt •Tourette's syndrome •use of sedatives •weight loss •an unusual or allergic reaction to bupropion, previous heart attack, treated with medication •heart disease, such as anorexia or bulimia •bipolar disorder or psychosis •diabetes or high blood sugar, or preservatives •breast-feeding •pregnant or trying to become pregnant How should you take Zyban (Wellabutrin)?Treatment with this drug begins while you are still smoking. Zyban (Wellabutrin) needs about a week to reach an effective level in your body; so to improve your chance of success, you should not attempt to quit until the second week of treatment. Set a firm date for quitting. If you are still smoking after that date, your odds of breaking the habit will be worse. You should keep taking Zyban (Bupropion) for 7 to 12 weeks. You can use nicotine patches along with Zyban (Wellabutrin). However, combining the two treatments can raise your blood pressure, so it's important to tell your doctor if you plan to use both. Do not smoke while using a patch, because too much nicotine can cause serious side effects. Participating in a counseling or support program will make success more likely. Your doctor can recommend a local program for you. Swallow Zyban (Wellabutrin) tablets whole. Do not chew, divide, or crush them. Take them exactly as prescribed. --If you miss a dose... Do not take an extra tablet to "catch up" for the missed dose. Skip the dose and take your next tablet at the regularly scheduled time. How does it work?Zyban tablets contain the active ingredient bupropion hydrochloride, which is a medicine used to help people who are dependant on nicotine to give up smoking. It acts in the brain but is not the same as nicotine replacement therapy.It is not fully understood how this medicine works to help people give up smoking, but it is known that bupropion affects neurotransmitters in the brain. Neurotransmitters are chemicals that are stored in nerve cells and are involved in transmitting messages between the nerve cells. Neurotransmitters are released from nerve cells as a message is transmitted. Once the message has been transmitted, the nerve cells then reabsorb the neurotransmitter. Bupropion prevents two of these neurotransmitters, noradrenaline and dopamine, from being reabsorbed back into the nerve cells. Noradrenaline and dopamine are responsible for moderating mood and various other processes in the brain. It is thought that bupropion helps people to quit smoking by increasing the amount of noradrenaline and dopamine free to act in the brain. Bupropion is used in combination with motivational support techniques. You should seek help and support as much as possible while giving up smoking, even while taking this medicine, as this will increase your chance of success. You should start taking this medicine while you are still smoking and set a 'target stop date' for within the first two weeks of treatment, preferably in the second week. This is because the medicine needs time to start working. The starting dose is one tablet once a day for six days, increasing on day seven to one tablet twice a day. There should be an interval of at least eight hours between doses. It is best to take your first dose when you get up in the morning and your second dose at least eight hours later. Try to avoid taking your second dose at bedtime, as difficulty sleeping (insomnia) is a common side effect of the medicine. If you have not managed to stop smoking by the seventh week of treatment, your doctor will ask you to stop taking this medicine. How to use Zyban (Wellabutrin) Sustained-Release Tablets:Use Zyban (Wellabutrin) Sustained-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Zyban (Wellabutrin) Sustained-Release Tablets. What side effects may I notice from taking bupropion?Side effects that you should report to your prescriber or health care professional as soon as possible: Uncommon: •blurred vision •difficulty breathing or wheezing •fast or irregular heartbeat (palpitations) •increased blood pressure •hallucinations •redness, especially in the first week of treatment or when doses are changed •confusion •seizures •skin rash, itching, or restlessness, anxiety, including inside the mouth •unusual tiredness or weakness More common: •agitation, peeling or loosening of the skin, blistering, hives •vomiting Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): Less common: •loss of appetite •loss of sexual drive •menstrual changes More common: •change in taste •constipation •difficulty sleeping •dizziness •dry mouth •headache •increased sweating •nausea •tremor •weight loss |
