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Quetiapine Fumarate 
DescriptionSeroquel (Quetiapine Fumarate) is a psychotropic medication shown to be effective in the treatment of many symptoms of schizophrenia, as well as in the treatment of acute mania associated with bipolar I disorder.
Quetiapine Fumarate (generic Seroquel) Reviewgeneric name: QuetiapineWhy is Seroquel prescribed?Seroquel is prescribed for the treatment of schizophrenia, a mental disorder marked by delusions (false beliefs), hallucinations, disrupted thinking, and loss of contact with reality. It is also used for the short-term treatment of mania associated with bipolar disorder. Seroquel is the first in a new class of antipsychotic medications. Researchers believe that it works by diminishing the action of dopamine and serotonin, two of the brain's chief chemical messengers. How should you take Seroquel?Your doctor will increase your dose gradually until the drug takes effect. If you stop Seroquel for more than 1 week, you'll need to build up to your ideal dosage once again. --If you miss a dose... Take it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once. --Storage instructions... Store at room temperature. Recommended dosageSCHIZOPHRENIA Adults The usual dosage range is 300 to 400 milligrams a day, divided into two or three smaller doses. Doses as low as 150 milligrams a day sometimes prove effective, and the dose rarely exceeds 750 milligrams per day. Doses above 800 milligrams per day have not been tested for safety. The dose is gradually increased over 4 days until the most effective dose is reached, using the following schedule: Day 1: Take 25 milligrams twice a day. Days 2, and 4: The doctor will increase each daily dose by 25 to 50 milligrams, 3, taken either two or three times a day. Day 5 and up: If needed, the doctor may increase each dose by 25 to 50 milligrams every 2 or more days. Adults The usual dosage range is 400 to 800 milligrams a day. Doses above 800 milligrams a day have not been tested for safety. The dosage will be gradually increased over 4 to 6 days until the most effective dose is reached, using the following schedule: Day 1: Take 50 milligrams twice a day. Day 2: The doctor will increase the dose to 100 milligrams twice a day. Day 3: The doctor will increase the dose to 150 milligrams twice a day. Day 4: The doctor will increase the dose to 200 milligrams twice a day. Days 5 and 6: If needed, the doctor may increase each dose by no more than 200-milligram increments to a total daily dose of 800 milligrams. DOSAGE ADJUSTMENT If you have liver problems, you may be started at 25 milligrams a day. The doctor will increase the dose as needed in increments of 25 to 50 milligrams a day based on your body's response. The dosage may also need to be lowered if you are weak, elderly, or prone to low blood pressure reactions. You may also need your dose adjusted if you're taking certain drugs, Tegretol, including Dilantin, and phenobarbital. Special information if you are pregnant or breastfeedingThe possibility of harm to a developing baby has not been ruled out. You should take Seroquel during pregnancy only if the benefits outweigh this potential risk. Notify your doctor as soon as you become pregnant or decide to become pregnant. It is not known whether Seroquel appears in breast milk, and breastfeeding is not recommended. Why should Seroquel not be prescribed?If Seroquel gives you an allergic reaction, you will not be able to use this drug. What side effects may occur?Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Seroquel.
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