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EzetimibeDescriptionZetia is used either alone or with other cholesterol lowering drugs (e.g., HMG-CoA reductase inhibitors or statins), along with a cholesterol-lowering diet, to help lower cholesterol in the blood
Ezetimibe (generic Zetia) Reviewgeneric name: EzetimibeWhy is Zetia prescribed?Zetia is a new kind of cholesterol-lowering drug. The older cholesterol-lowering drugs called "statins" reduce cholesterol by interfering with its production in the body. Zetia acts by diminishing the absorption of dietary cholesterol through the intestines. Zetia may be taken alone or with a statin drug. Because the two drugs fight cholesterol in different ways, the Zetia/statin combination has a greater impact than either drug alone. Cholesterol--especially "bad" LDL cholesterol--promotes clogged arteries, increasing the risk of heart attack and stroke. "Good" HDL cholesterol helps to prevent clogged arteries. Zetia lowers the bad cholesterol and raises the good. It also lowers total cholesterol readings and reduces levels of triglycerides (fats in the blood). Cholesterol-lowering drugs are typically prescribed for people who either have heart disease or are in danger of developing it. For people at high risk of heart disease, current guidelines call for considering drug therapy when LDL levels reach 130. For people at lower risk, the cut-off is 160. For those at little or no risk, it's 190. Most important fact about ZetiaDoctors usually prescribe cholesterol-lowering drugs only after changes in lifestyle have failed to bring cholesterol down to a healthy level. These changes include following a diet low in fat and cholesterol and high in fiber, shedding excess weight, and getting more exercise. It's important to remember that drug therapy is a supplement to--not a substitute for--these other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program recommended by your doctor. Why should Zetia not be prescribed?If Zetia causes an allergic reaction, you'll be unable to use it. Combined therapy with Zetia and a statin drug should be avoided if you have a liver condition or are pregnant or nursing. OverdosageThere is no experience with Zetia overdose. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately. What side effects may occur?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Zetia.
Certain allergic reactions such as hives have also occurred. Other side effects that occur when Zetia is taken with a statin drug include chest pain, muscle pain, headache, dizziness, and upper respiratory infection. Special warnings about ZetiaZetia is not recommended for people with moderate to severe liver disease, or for children under 10. |









