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Amiloride And Hydrochlorothiazide

 

Amiloride And Hydrochlorothiazide Review

brand names: Ezide, Esidrix, HydroDIURIL, Oretic, Microzide
generic names: Hydrochlorothiazide, hydrochlorothiazide, Hydrochlorothiazide Capsules,, Amiloride hydrochloride

How does it work?

Carace plus tablets contain two active ingredients, lisinopril and hydrochlorothiazide. Lisinopril is a type of medicine called an ACE inhibitor. Hydrochlorothiazide is a type of medicine called a thiazide diuretic. These are both medicines used to lower high blood pressure.

ACE inhibitors such as lisinopril work by blocking the action of a compound in the body called angiotensin converting enzyme (ACE). Normally ACE produces another compound called angiotensin II, as part of the body's natural control of blood pressure. Angiotensin II causes blood vessels to constrict and narrow, which increases the pressure within the blood vessels.

As lisinopril blocks the action of ACE, it reduces the production of angiotensin II. This means that the blood vessels are allowed to relax and widen. The overall effect of this is a drop in blood pressure, hence lisinopril can be used to lower high blood pressure.

Diuretics such as hydrochlorothiazide are sometimes referred to as ‘water tablets’. They remove excess fluid from the body by increasing the production of urine.

Diuretics act in the kidneys. They work by causing the kidneys to increase the amount of salts, such as potassium and sodium, that are filtered out of the blood and into the urine. When these salts are filtered out of the blood by the kidneys, they draw water alongside them. As diuretics increase the removal of salts from the blood, they also cause more water to be drawn out of the blood and into the urine.

Removing water from the blood decreases the volume of fluid circulating through the blood vessels. This subsequently decreases the pressure within the blood vessels. Diuretics can therefore be used to lower high blood pressure.

The combination of lisinopril with hydrochlorothiazide is used when blood pressure has not been lowered sufficiently using lisinopril on its own.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
•diabetes
•gout
•kidney disease, sulfa drugs, other medicines, foods, dyes, or difficulty passing urine
•liver disease
•pancreatitis
•systemic lupus erythematosus (SLE)
•an unusual or allergic reaction to Hydrochlorothiazide (Amiloride), small amounts of urine

What does my medication look like?

HydroHydrochlorothiazide (Amiloride) is available with a prescription generically and under several brand names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Oretic 50 mg--white tablets
• Oretic 25 mg--white tablets
• HydroDIURIL 100 mg--round, peach-colored, scored, compressed tablets
• HydroDIURIL 50 mg--round, peach-colored, scored, compressed tablets
• HydroDIURIL 25 mg--round, peach-colored, scored, compressed tablets
• Esidrix 100 mg--round, blue, scored tablets
• Esidrix 50 mg--round, yellow, scored tablets
• Esidrix 25 mg--round, pink, scored tablets

• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, allergic reactions, drug interactions, warnings, precautions, directions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
• Remember, never share your medicines with others, keep this and all other medicines out of the reach of children, and use this medication only for the indication prescribed.

Copyright 1996-2006 Cerner Multum, Inc. Version: 6.01. Revision Date: 6/2/06 11:16:53 AM.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

• It is not known if lisinopril passes into breast milk, however Hydrochlorothiazide (Amiloride) does pass into breast milk. Breastfeeding mothers should therefore either stop breastfeeding while taking this medicine, or not take this medicine. Seek medical advice from your doctor.
  
  
• This medicine should not be used in pregnancy, particularly in the second and third trimesters, as it may be harmful to the unborn baby. Seek further medical advice from your doctor. If you get pregnant while taking this medicine, stop taking it and consult your doctor immediately. However, in some cases, where this medicine is considered to be life-saving to the mother, treatment may be continued.
  
  

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Overdosage

Any medication taken in excess can cause symptoms of overdose. If you suspect an overdose, seek medical attention immediately.

• Symptoms of HydroDIURIL overdose may include:
  Dry mouth, weak or irregular heartbeat, nausea and vomiting, muscle pain or cramps, excessive thirst, weakness and dizziness