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Trimethoprim and Sulfamethoxazole

 

Trimethoprim and Sulfamethoxazole (generic Bactrim) Review

brand names: Cotrim DS, Sulfatrim, Bactrim DS, Cotrim, Cotrima, Bethaprim, Septra DS, Co-trimoxazole, Bactrim, Septra
generic names: Trimethoprim, Sulfamethoxazole

Why is Bactrim prescribed?

Bactrim, an antibacterial combination drug, is prescribed for the treatment of certain urinary tract infections, severe middle ear infections in children, long-lasting or frequently recurring bronchitis in adults that has increased in seriousness, inflammation of the intestine due to a severe bacterial infection, and travelers' diarrhea in adults. Bactrim is also prescribed for the treatment of Pneumocystis carinii pneumonia, and for prevention of this type of pneumonia in people with weakened immune systems.

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

Sulfamethoxazole and trimethoprim side effects

Stop taking sulfamethoxazole and trimethoprim and seek emergency medical attention if you experience any of the following serious side effects:

• yellow skin or eyes.
• unusual bleeding or bruising; or
• an allergic reaction (difficulty breathing; or hives); swelling of your lips, tongue, or face; closing of your throat;

Other, less serious side effects may be more likely to occur. Continue to take your medication and talk to your doctor if you experience

• increased sensitivity to the sun.
• weakness; or
• nausea, decreased appetite, vomiting, or diarrhea;
• headache, fatigue, or dizziness;

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Most important fact about Bactrim (Trimethoprim)

Sulfamethoxazole, an ingredient in Bactrim, is one of a group of drugs called sulfonamides, which prevent the growth of bacteria in the body. Rare but sometimes fatal reactions have occurred with use of sulfonamides. These reactions include Stevens-Johnson syndrome (severe eruptions around the mouth, a severe blood disorder (agranulocytosis), sudden and severe liver damage, progressive disintegration of the outer layer of the skin, or eyes), anus, and a lack of red and white blood cells because of a bone marrow disorder.

Frequent blood counts by a doctor are recommended for patients taking sulfonamide drugs.

Notify your doctor at the first sign of an adverse reaction such as reddish or purplish skin spots, abnormal skin paleness, shortness of breath, cough, joint pain, fever, sore throat, skin rash, or yellowing of the skin or whites of the eyes.

How should I take this medicine?

Take SMX-TMP by mouth. Follow the directions on the prescription label. Take with a full glass of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course of medicine prescribed by your prescriber or health care professional even if you feel better.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Bactrim (Trimethoprim).

• More common side effects may include:
  Hives, skin rash, nausea, lack or loss of appetite, vomiting