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Adapalene Topical Gel

 

Adapalene Topical Gel (generic Differin) Review

brand name: Differin
generic names: Adapalene, Adapalene Topical

Differin Pads is used for:

Treating acne. It may also be used for other conditions as determined by your doctor.

Differin Pads is a retinoid-like medicine. It works by decreasing acne formation.

Warning!

• This medicine may be harmful to an unborn baby. Women of child-bearing age should use a reliable contraceptive method to prevent pregnancy while using this medicine.
  
  
• Avoid use of this product on large areas of skin, as this may result in absorption of sufficient quantities to cause adverse effects.
  
  
• Avoid use on broken or inflamed skin.
  
  
• Avoid contact with mouth and mucous membranes.
  
  
• Avoid contact with eyes
  
  
• Avoid exposure to sunlight or sunlamps while using this medicine, as it increases the sensitivity of your skin. If exposure to sunlight cannot be avoided, use protective measures such as sun-creams or protective clothing.
  
  

What side effects may I notice from using adapalene?

Side effects that you should report to your prescriber or health care professional as soon as possible:
•severe burning, and irritated skin, inflamed, or swelling of the treated areas

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
•increased sensitivity to the sun
•mild burning or stinging
•red, crusting, reddening, itching, the skin may peel after a few days

Possible food and drug interactions when taking Differin (Adapalene)

Avoid using Differin (Adapalene) with any other product that can irritate the skin, such as spices, astringents, and products with high concentrations of alcohol, soaps and cosmetics that have a strong drying effect, medicated soaps and cleansers, and lime.

Special caution is necessary if you have used, or are currently using, any skin product containing sulfur, resorcinol, or salicylic acid. Do not use such a product with Differin (Adapalene). If you have used one of these products recently, do not begin Differin treatment until the effects of the other product have subsided.

General information:

• If your symptoms do not improve or if they become worse, check with your doctor.
• Differin (Adapalene) Pads is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If you have any questions about Differin (Adapalene) Pads, pharmacist, please talk with your doctor, or other health care provider.

This information is a summary only. It does not contain all information about Differin (Adapalene) Pads. If you have questions about the medicine you are taking or would like more information, pharmacist, check with your doctor, or other health care provider.

Issue Date: September 5, 2007 Database Edition 07.3.1.003 Copyright © 2007 Wolters Kluwer Health, Inc.

How does it work?

Adapalene has actions similar to vitamin A (retinol). It stimulates cell division in the skin and reduces the production of keratin. It aids skin peeling and prevents the formation of acne lesions (comedones).

Acne is caused by blockage of sebaceous glands. This leads to an accumulation of the skins natural oils (sebum). Bacteria on the skin feed on sebum and produce waste products which further inflame the sebaceous glands, causing acne. Irritant substances can leak into the surrounding skin causing further inflammation.

The action of adapalene combats the changes that take place in acne.

Adapalene is used in the treatment of mild to moderate acne. It is best suited to dry and fair skin.